inc igvtm500ml 35403 ido1 inhibitor indoximod medchemexpress hy  (MedChemExpress)

Journal: iScience

Article Title: Differential immunometabolic responses to Delta and Omicron SARS-CoV-2 variants in golden syrian hamsters

doi: 10.1016/j.isci.2024.110501

Figure Lengend Snippet: Effect of IL-10 and IFN-g on SARS-CoV-2 replication and SARS-CoV-2-induced cytokines, ISGs/chemokines, and IDO1 in Calu-3 cells Calu-3 cells were pretreated with IL-10 (A) or IFN-g (B) for 1 h and infected with SARS-CoV-2 (delta variant) with 0.01 MOI for 48 h. RNA was isolated from cell lysate and culture supernatant and analyzed for viral RNA copies using E gene-specific primers and probes by RT-qPCR (A and B). Total cellular RNA was reverse transcribed to cDNA, and gene expression of host genes was analyzed by RT-qPCR (C and D). Data represent the mean ± SEM. ∗ p < 0.05, 0.01 MOI vs. 0.01 MOI + IFN-γ. ns, non-significant.

Article Snippet: IDO1 inhibitor (Indoximod) , MedChemExpress , HY-16724.

Techniques: Infection, Variant Assay, Isolation, Quantitative RT-PCR, Reverse Transcription, Expressing

Journal: iScience

Article Title: Differential immunometabolic responses to Delta and Omicron SARS-CoV-2 variants in golden syrian hamsters

doi: 10.1016/j.isci.2024.110501

Figure Lengend Snippet:

Article Snippet: IDO1 inhibitor (Indoximod) , MedChemExpress , HY-16724.

Techniques: Virus, Variant Assay, Recombinant, Avidin-Biotin Assay, Plasmid Preparation, Software